WHO classification of tumours of bone

Cartilage tumors
  • osteochondroma
  • enchondroma
  • periosteal chondroma
  • multiple chondromatosis
  • chondroblastoma
  • chondromyxoid fibroma
  • synovial chondromatosis
  • primary chondrosarcoma
  • periosteal chondrosarcoma
  • dedifferentiated chondrosarcoma
  • mesenchymal chondrosarcoma
  • clear cell chondrosarcoma
  • secondary chondrosarcoma
Osteogenic tumours
  • osteoid osteoma
  • osteoblastoma
  • conventional osteosarcoma
  • talangiectatic osteosarcoma
  • small cell osteosarcoma
  • low grade central osteosarcoma
  • secondary osteosarcoma
  • parosteal osteosarcoma
  • periosteal osteosarcoma
  • high grade surface osteosarcoma
Fibrogenic tumors
  • desmoplastic firbroma
  • fibrosarcoma
Fibrohistiocytic tumors
  • benign fibrous histiocytoma
  • malignant fibrous histiocytoma
Ewing sarcoma
Haematopoitic tumors
  • plasma cell myeloma
  • malignant lymphoma
Giant cell tumor
  • giant cell tumor of bone
  • malignancy in giant cell tumor
chordoma
Vascular tumors
  • haemangioma
  • angiosarcoma
Myogenic, lipogenic, neural, and epithelial tumors
  • leiomyoma (no cases)
  • leiomyosarcoma
  • lipoma
  • liposarcoma
  • schwannoma
  • adamantinoma
Tumors of undefined neoplastic nature
  • aneurysmal bone cyst
  • simple bone cyst
  • fibrous dysplasia
  • osteofibrous dysplasia
  • Langerhans cell histiocytosis
Others not listed in WHO classifications
  • benign bone tumor (undefined)
  • intermediate tumors of bone (undefined)
  • malignant bone tumor (undefined)
  • malignant stromal tumor of bone
  • radiation induced sarcoma
  • spindle cell sarcomas of bone
  • undifferentiated sarcoma of bone
  • alveolar soft part sarcoma of bone
  • unknow lesions



WHO classification of tumours of soft tissue (2013)

Adipocytic Tumours
  • Lipoma
  • Lipomatosis
  • Lipomatosis of nerve
  • Lipoblastoma/lipoblastomatosis
  • Angiolipoma
  • Myolipoma
  • Chondroid lipoma
  • Extra-renal angiomyolipoma
  • Extra-adrenal myelolipoma
  • Spindle cell/pleomorphic lipoma
  • Hibemoma
  • Atypical lipomatous Tumour/ well differentiated liposarcoma
  • Dedifferentiated liposarcoma
  • Myxoid liposarcoma
  • Pleomorphic liposarcoma
  • Liposarcoma, not otherwise specified
Fibroblastic/Myofibroblastic Tumours
  • Nodular fasciitis
  • Proliferative fasciitis
  • Proliferative myositis
  • Myositis ossificans
  • Fibro-osseous pseudotumour of digits
  • Ischaemic fasciitis
  • Elastofibroma
  • Fibrous hamartoma of infancy
  • Fibromatosis colli
  • Juvenile hyaline fibromatosis
  • Inclusion body fibromatosis
  • Fibroma of tendon sheath
  • Desmoplastic fibroblastoma
  • Mammary-type myofibroblastoma
  • Calcifying aponeurotic fibroma
  • Angiomyofibroblastoma
  • Cellular angiofibroma
  • Nuchal-type fibroma
  • Gardner fibroma
  • Calcifying fibrous tumour
  • Palmar/Plantar firomatosis
  • Desmoid-type fibromatosis
  • Lipofibromatosis
  • Giant Cell Fibroblastoma
  • Dermatofibrosarcoma protuberans
  •         Fibrosarcomatous dermatofibrosarcoma protuberans
  •         Pigmented dermatofibrosarcoma protuberans
  • Solitary fibrous tumour
  •         Solitary fibrous tumour, malignant
  • Inflammatory myofibroblastic Tumour
  • Low-grade myofibroblastic sarcoma
  • Myxoinflammatory fibroblastic sarcoma/ Atypical myxoinflammatory fibroblastic tumour
  • Infantile fibrosarcoma
  • Adult fibrosarcoma
  • Myxofibrosarcoma
  • Low-grade fibromyxoid sarcoma
  • Sclerosing epithelioid fibrosarcoma
So-Called Fibrohistiocytic Tumours
  • Tenosynovial giant cell tumour(localized type)
  • Tenosynovial giant cell tumour(diffused type)
  • Tenosynovial giant cell tumour(malignant type)
  • Deep benign fibrous Histiocytoma
  • Plexiform fibrohistiocytic tumour
  • Giant cell tumour of soft tissues
Smooth Muscle Tumours
  • Deep leiomyoma
  • Leiomyosarcoma (excluding skin)
Pericytic(Perivascular) Tumours
  • Glomus tumour (and variants)
  •         Glomangiomatosis
  •         Malignant glomus tumour
  • Myopericytoma
  •         Myofibroma
  •         Myofibromatosis
  • Angioleiomyoma
Skeletal Muscle Tumours
  • Rhabdomyoma
  •         Adult type
  •         Fetal type
  •         Genital type
  • Embryonal rhabdomyosarcoma (including botryoid,anaplastic)
  • Alveolar rhabdomyosarcoma (including solid,anaplastic)
  • Pleomorphic rhabdomyosarcoma
  • Spindle cell/sclerosing rhabdomyosarcoma
Vascular Tumours Of Soft Tissue
  • Heamangioma
  •         Synovial
  •         Venous
  •         Arteriovenous haemangioma/malformation intramuscular
  •         Intramuscular
  • Epithelioid haemangioma
  • Angiomatosis
  • Lymphangioma
  • Kaposiform haemangioendothelioma
  • Retiform haemangioendothelioma
  • Papillary intralymphatic angioendothelioma
  • Composite haemangioendothelioma
  • Pseudomyogenic (epithelioid sarcoma-like) haemangioendothelioma
  • Kaposi sarcoma
  • Epithelioid haemangioendothelioma
  • Angiosarcoma of soft tissue
  • Soft tissue chondroma
  • Extraskeletal mesenchymal chondrosarcoma
  • Extraskeletal osteosarcoma
Gastrointestinal Stromal Tumours
  • Benign gastroinstestinal stromal tumour
  • Gastrointestinal stromal tumour, uncertain malignant potential
  • Gastrointestinal stromal tumour, malignant
Nerve Sheath Tumours
  • Schwannoma (including variants)
  • Melanotic schwannoma
  • Neurofibroma (incl. variants)
  •         Plexiform neurofibroma
  • Perineurioma
  •         Malignant perineurioma
  • Granular cell tumour
  • Dermal nerve sheath myxoma
  • Solitary circumscribed neuroma
  • Ectopic meningioma
  • Nesal glial heterotopia
  • Benign triton tumour
  • Hybrid nerve sheath tumours
  • Malignant peripheral nerve sheath tumour
  • Epithelioid Malignant Peripheral Nerve Sheath Tumour
  • Malignant triton tumour
  • Malignant granular cell tumour
  • Ectomesenchymoma
Tumours Of Uncertain Differentiation
  • Acral Fibromyxoma
  • Intramuscular myxoma (including cellular variant)
  • Juxta-articular myxoma
  • Deep ("Aggressive") angiomyxoma
  • Pleomorphic hyalinizing angiectatic Tumour
  • Ectopic hamartomatous thymoma
  • Haemosiderotic fibrolipomatous tunour
  • Atypical fibrosanthoma
  • Angiomatoid fibrous histiocytoma
  • Ossifying fibromyxoid tumour
  •         Ossifying fibromyxoid tumour, malignant
  • Mixed Tumour NOS
  • Mixed Tumour NOS, malignant
  • Myoepithelioma
  • Myoepithelial carcinamoa
  • Phosphaturic mesenchymal tumour, benign
  • Phosphaturic mesenchymal tumour, malignant
  • Synovial sarcoma NOS
  •         Synoval sarcoma, spindle cell
  •         Synoval sarcoma, biphasic
  • Epithelioid sarcoma
  • Alveolar soft-part sarcoma
  • Clear cell sarcoma of soft tissue
  • Extraskeletal myxoid chondrosarcoma
  • Extraskeletal Ewing sarcoma
  • Desmoplastic small round cell tumour
  • Extrarenal rhabdoid turmour
  • Neoplasms with perivascular epithelioid cell differentiation (PEComa)
  •         PEComa NOS, benign
  •         PEComa NOS, malignant
  • Intimal sarcoma
Undifferentiated/Unclassified Sarcomas
  • Undifferentiated spindle cell sarcoma
  • Undifferentiated pleomorphic sarcoma
  • Undifferentiated round cell sarcoma
  • Undifferentiated epithelioid sarcoma
  • Undifferentiated sarcoma NOS
Others not listed in WHO classifications
  • Parachordoma
  • Malignant mesenchymoma
  • Metastatic Malignancy of Soft Tissue
  • Malignant Lymphoma of Soft Tissue
  • Radiation-induced Sarcoma of Soft Tissue
  • Alveolar Sarcoma Of Soft Tissue
  • Malignant Tumour of Soft Tissue (Uncertain Type)
  • Intermediate Tumour of Soft Tissue (Uncertain Type)
  • Benign Tumour of Soft Tissue (Uncertain Type)
  • Uncertain Tumour Of Soft Tissue

Related topics

If you have any question or suggestion, Please feel free to contact us. We will try to help.